I don't hesitate to paint my nails with glitter anymore because I know that if I use this method, it won't be annoying to remove.
The glitter that I'm removing is China Glaze - It's A Trap-eze. It's extremely chunky glitter, as you can see below.
|China Glaze It's A Trap-eze|
I have pretty dry and flakey nails and I find that this doesn't make them worse. So as far as I can tell, it's not harming your nails.